(11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione; Sch-32088, Elocon, Nasonex; Twisthaler; Asmanex; Ecural; Elocom
A topical corticosteroid used as an anti-inflammatory.
Synonyms
(11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione; Sch-32088, Elocon, Nasonex; Twisthaler; Asmanex; Ecural; Elocom
Molecular Formula
C27H30Cl2O6
Melting Point
>209°C (dec.)
Solubility
Chloroform (Slightly), Dioxane (Slightly, Sonicated), Methanol (Slightly, Heated)
Method for Determining Identity
lH NMR Spectroscopic Analysis
TLC Conditions
SiO2; Dichloromethane: methanol = 10: 1; Visualized with UV and AMCS; Single spot; Rf=0.55.
Appearance
Supplied as a white to off-white solid
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.