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M4470-01B Rabbit Anti-MCT1, CT (Monocarboxylate Transporter 1, MCT 1, Solute Carrier Family 16 Member 1, SLC16A1)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P53985
Isotype
IgG
Grade
Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_003042
Gene ID
6566
Shipping Temp
Blue Ice
Storage Temp
-20°C

SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT.

Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Positive Control
T47D cell lysates
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 430-460 in the C-terminal region of human MCT1.Cellular Localization: Cell membrane; Multi-pass membrane protein
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human SLC16A1 at ~53kD.
References
1. Pinheiro,C., Virchows Arch. 452(2), 139-146 (2008). 2. Otonkoski,T., Am. J. Hum. Genet. 81(3), 467-474 (2007). 3. Martin-Venegas,R., J. Nutr. 137(1), 49-54 (2007).
USBio References
No references available
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