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M4692-59D Rabbit Anti-MSRA, NT (Methionine Sulfoxide Reductase A, Peptide Methionine Sulfoxide Reductase, Peptide-methionine (S)-S-oxide Reductase, Peptide Met(O) Reductase, Protein-methionine-S-oxide Reductase, PMSR)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9UJ68
Isotype
IgG
Grade
Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_036463
Shipping Temp
Blue Ice
Storage Temp
-20°C
EC=1.8.4.11

MSRA is ubiquitous and highly conserved. This protein carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein's proposed function is the repair of oxidative damage to proteins to restore biological activity.

Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide selected from the N-terminal region of human MSRA (KLH).
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human MSRA. Species Crossreactivity: mouse.
References
1.Pascual,I., Larrayoz,I.M. Genomics 93(1), 62-71 (2009). 2.Schallreuter,K.U., Rubsam,K. J. Invest. Dermatol. 128(4), 808-815 (2008). 3.Picot,C.R., Perichon,M. FEBS Lett. 558(1-3), 74-78 (2004). 4.Vougier,S., Mary,J. Biochem. J. 373(PT 2), 531-537 (2003).
USBio References
No references available
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