S- CAS 54-11-5

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N2561-90G S-(-)-Nicotine ((-)-1-Methyl-2-[3-pyridyl]pyrrolidine, 3-[(2S)-1-Methyl-2-pyrrolidinyl]pyridine; (-)-Nicotine, Exodus, Nicolan, Niconil, Nicopatch, Nicorette; Nicotell TTS, Nicotin; l-Nicotine) CAS: 54-11-5

Specifications

References

CAS Number

54-11-5

Grade

Highly Purified

Molecular Formula

C10H14N2

Molecular Weight

162.23

EU Commodity Code

38220090

Shipping Temp

Storage Temp

-20°C

(-)-1-Methyl-2-[3-pyridyl]pyrrolidine, 3-[(2S)-1-Methyl-2-pyrrolidinyl]pyridine; (-)-Nicotine, Exodus, Nicolan, Niconil, Nicopatch, Nicorette; Nicotell TTS, Nicotin; l-Nicotine)

Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.

Solubility: Methanol

Method for Determining Identity: Proton NMR spectroscopic analysis.

TLC Conditions: SiO2; Dichloromethane: Methanol: NH4OH; 9ml: 1ml: 3 drops. Visualized with UV; Single spot; Rf=0.3

Specific Rotation: -128°C (c=0.2; Methanol)

Storage and Stability

May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

Geffken, D., et al.: Am. J. Epidemiol., 153, 242 (2001), Bolego, C., et al.: Cardiovasc. Res., 53, 568 (2002), Leone, A., et al.: Curr. Pharm. Des., 1, 2199 (2005)