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N2561-90P S-(-)-Nicotine Ditartrate Dihydrate CAS: 6019-06-3

Specifications
References
CAS Number
6019-06-3
Grade
Highly Purified
MDL Number
MFCD00150899
Molecular Formula
C₁₀H₁₄N₂•2(C₄H₆O₆)•2(H₂O)
Molecular Weight
498.44
EU Commodity Code
38220090
UN DOT Shipping
UN1659 PGII
Shipping Temp
Blue Ice
Storage Temp
-20°C
3-[(2S)-1-Methyl-2-pyrrolidinyl]pyridine (2R,3R)-2,3-Dihydroxybutanedioate Hydrate; |Nicotine Tartrate Dihydrate; (S)-3-(1-Methyl-2-pyrrolidinyl)pyridine (2R,3R)-2,3-Dihydroxybutanedioate Dihydrate; (S)-3-(1-methyl-2-pyrrolidinyl)pyridine [R-(R*,R*)]-2,3-Dihydroxybutanedioate Dihydrate; (-)-Nicotine Di-(+)-Hydrogen Tartrate

Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer. It is a potent neurotoxin.

Synonyms
3-[(2S)-1-Methyl-2-pyrrolidinyl]pyridine (2R,3R)-2,3-Dihydroxybutanedioate Hydrate; Nicotine Tartrate Dihydrate; (S)-3-(1-Methyl-2-pyrrolidinyl)pyridine (2R,3R)-2,3-Dihydroxybutanedioate Dihydrate; (S)-3-(1-methyl-2-pyrrolidinyl)pyridine [R-(R*,R*)]-2,3-Dihydroxybutanedioate Dihydrate; (-)-Nicotine Di-(+)-Hydrogen Tartrate
CAS No
6019-06-3 65-31-6-for anhydrous
Molecular Formula
C₁₀H₁₄N₂•2(C₄H₆O₆)•2(H₂O)
Molecular Weight
498.44
Appearance
White solid
Purity (HPLC)
≥98%
Specific Rotation [a]20/D, C=10, H2O
+23.0 to +27.0 deg
Melting Point
97-100°C
Water
6.7-8.0%
Solubility
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Ferretti, G., et al.: J. Med. Chem., 45, 4724 (2002), Guillen, M., et al.: J. Agric. Food Chem., 53, 1093 (2005), Ramunno, A., et al.: Bioorg. Med. Chem. Lett., 15, 3237 (2005), Alburges, M., et al.: Eur. J. Pharmacol., 573, 124 (2007)
USBio References
No references available
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