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O7024 Ophiobolin A (Cochliobolin A, Ophiobolin, Ophiobalin) CAS: 4611-05-6

Specifications
References
CAS Number
4611-05-6
Grade
Highly Purified
Molecular Formula
C25H36O4
Molecular Weight
400.6
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
Cochliobolin A, Ophiobolin, Ophiobalin

Ophiobolin A is the dominant member of a class of phytotoxic metabolites produced by plant pathogenic fungi. Ophiobolin A acts as an inhibitor of calmodulin action in calcium regulation. In-house testing at Microbial Screening Technologies has shown that ophiobolin A possesses a broad biological profile with antibacterial, antifungal, antitumor and nematocidal activiites.

Purity: >95% by HPLC
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Related to: Ophiobolin B
Source
Bipolaris leersia
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis. Quetglas S. |EMBO J. 2002, 21, 3970. |2. The biology of ophiobolins. Au T.K. et al. Life Sci. 2000, 67, 733.
USBio References
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