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P3000-50 Pancreatin, Porcine Pancreas CAS: 8049-47-6

Specifications
References
CAS Number
8049-47-6
Grade
Reagent Grade
MDL Number
MFCD00131789
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C

Hydrolyzes starch into dextrins and sugar Pancreatin from porcine pancreas is used in the treatment of steatorrhea by lipase supplementation therapy and for pancreatic diabetes. It is also used in the removal of formalin-fixed tissues from arterial grafts without causing damage in fiber integrity. Further, it finds uses in contact lenses. In addition to this, it hydrolyzes starch into dextrins and sugar. It is also used to treat conditions responsible for deficiency in pancreatic secretions, such as surgical pancreatectomy, pancreatitis and cystic fibrosis.

EC No
232-468-9
CAS No
8049-47-6
Source
Porcine pancreas
Appearance
Yellow to tan powder. Contains lactose or sucrose as extender (sucrose may contain up to 3.25% starch.)
Purity
Contains many enzymes, including amylase, trypsin, lipase, ribonuclease and protease. The National Formulary (N.F.) and the U.S. Pharmacopeia (USP) specify amylase, protease and lipase only.
Loss on Drying
≤1%
Fat
≤1%
Amylase
≥2units/mg
Lipase
≥2units/mg
Protease
≥2units/mg
Unit Definition
Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than 2 microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.
Solubility
Soluble in water. Insoluble in alcohol and ether.
Storage and Stability
Lyophilized powder is stable for 6 months after receipt at -20°C.
Important Note
Toxicity and Hazards
 
References
Aschoff, J. K.; Rolke, C. L.; Breusing, N.; Bosy-Westphal, A.; Högel, J.; Carle, R.; Schweiggert, R. M. Bioavailability of beta-cryptoxanthin is greater from pasteurized orange juice than from fresh oranges-a randomized cross-over study. Mol. Nutr. Food Res. 2015, 59 (10), 1896-1904.|.|Ma, X.; Yang, S. T.; Tang, H.; Liu, Y.; Wang, H. Competitive adsorption of heavy metal ions on carbon nanotubes and the desorption in simulated biofluids. J. Colloid Interface Sci. 2015, 448, 347-355.
USBio References
No references available
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