(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Potassium Salt; Penicillin G Potassium Salt; Benzylpenicillin Potassium; Cosmopen; Cristapen; Crytapen; Eskacillin; Falapen; Forpen; Hipercilina; Hyasorb; Hylenta; M-Cillin; Monopen; NSC 131815; Notaral; Pentid; Pentids; Potassium 6-(Phenylacetamido)penicillanate; Potassium Benzylpenicillin; Potassium Benzylpenicillinate; Potassium Penicillin G; Scotcil; Tabilin
Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci† and the penicillin-induced lysis of Streptococcus mutans
Effective against Gram-positive bacteria. Blocks cell wall formation in growing cells, resulting in accumulation of uracil nucleotides of muramic acid peptides. Acts at the final stage of cell wall synthesis and prevents cross-linking of peptidoglycan strands.
Appearance
White to off-white powder
Potency
1440-1680 units/mg
Absorption
(264nm): 0.80 to 0.88 (280nm): ≤0.10 (325nm): ≤ 0.10
Penicillin Polymer
≤0.08%
Solubility
100mg/ml in water
Storage and Stability
Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The potassium salt is soluble in H2O at 100mg/ml.
Conforms to USP/BP specifications
Form
White to off-white powder
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
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