Pimprinine CAS 13640-26-1

Subscribe to our newsletter!

Welcome | LOG OUT

P4186-68 Pimprinine (5-(3-Indolyl)-2-methyloxazole, Antibiotic WS 30581C, Antibiotic APHE 3) CAS: 13640-26-1

Specifications

References

CAS Number

13640-26-1

Grade

Highly Purified

Molecular Formula

C12H10N2O

Molecular Weight

198.2

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

5-(3-Indolyl)-2-methyloxazole, Antibiotic WS 30581C, Antibiotic APHE 3

Pimprinine is an indole alkaloid produced by many species of Streptomyces. Pimprinine is a potent inhibitor of monoamine oxidase and has shown antiepileptic effects. More recently, pimprinine showed promising anticonvulsant activity in electric seizure threshold tests in mice, comparable to phenyl hydantoin. Pimprinine also inhibited tremorine-induced tremors and analgesia in mice.

Purity: >95% by HPLC

Solubility: Soluble in ethanol, methanol, DMF or DMSO

Related to: Indolmycin

Source

Streptomyces sp.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

1. Isolation, characterization and synthesis of pimprinine, pimprinethine and pimprinaphine, metabolites of |Streptoverticillium olivoreticuli. Koyama Y. et al. Agri. Biol. Chem. 1981, 45, 1285. |2. Pimprinine, an extracellular alkaloid produced by Streptomyces CDRIL-312: fermentation, isolation and |pharmacological activity. Naik S.R. et al. J. Biotechnol. 2001, 88, 1.