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P5750-50C Goat Anti-PRDM10 (PR Domain Zinc Finger Protein 10, PR Domain-containing Protein 10, Tristanin, KIAA1231, PFM7, TRIS)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Bo Ca Hu
Accession #
NP_064613.2, NP_955469.1, NP_955470.1
Gene ID
56980
Shipping Temp
Blue Ice
Storage Temp
-20°C

The PRDM10 protein is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:32,000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-NGNGSSEVHITKP, from PRDM10, at C-terminal (NP_064613.2, NP_955469.1, NP_955470.1).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes PRDM10. Species sequence homology: Bovine, canine and human.
References
1. Alvarez-Venegas R, Avramova Z. SET-domain proteins of the Su(var)3-9, E(z) and trithorax families. Gene. 2002 Feb 20;285(1-2):25-37.
USBio References
No references available
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