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P9102-71M-PE Rabbit Anti-PGP9.5, CT (Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1, UCH-L1, Ubiquitin Thiolesterase L1, Neuron Cytoplasmic Protein 9.5, UCHL1) (PE)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P09936
Conjugate
PE
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA IF IHC WB
Crossreactivity
Hu Mo Rt
Accession #
NP_004172
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Notes
Preservative Free

UCHL1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons (Doran et al., 1983 [PubMed 6343558]).

Applications
Suitable for use in FLISA, Western Blot, Immunofluorescence and Immunohistochemistry. Other applications not tested.
Recommended Dilutions
Immunohistochemistry: Formalin fixed, paraffin embedded tissues Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 187-214 in the c-terminal region of human PGP9.5. Species Sequence Homology: bovine, equine, monkey and porcine.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human PGP9.5. Species Crossreactivity: mouse and rat.
References
1. Maraganore, D.M., et al., Mov Disord 18(6):631-636 (2003). 2. Nishikawa, K., et al., Biochem. Biophys. Res. Commun. 304(1):176-183 (2003). 3. Liu, Y., et al., Cell 111(2):209-218 (2002). 4. Caballero, O.L., et al., Oncogene 21(19):3003-3010 (2002). 5. Saigoh, K., et al., Nat. Genet. 23(1):47-51 (1999).
USBio References
No references available
Conjugates
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