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R1200-11B Goat Anti-RASA3 (Ras GTPase-activating Protein 3, RAS p21 Protein Activator 3, GAP1(IP4BP), GAP1IP4BP, GAPIII, Ins P4-binding Protein, MGC46517, MGC47588)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Ca Hu Mo Rt
Accession #
NP_031394.2
Gene ID
22821
Shipping Temp
Blue Ice
Storage Temp
-20°C

Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:32,000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-QYKRDKFKKTKYGSQ, from RASA3, at the internal region (near the C-terminal) of the protein (NP_031394.2).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes RASA3. Species sequence homology: Canine, human, mouse and rat.
References
1. Kuai J, Wooters J, Hall JP, Rao VR, Nickbarg E, Li B, Chatterjee-Kishore M, Qiu Y, Lin LL. NAK is recruited to the TNFR1 complex in a TNFalpha-dependent manner and mediates the production of RANTES: identification of endogenous TNFR-interacting proteins by a proteomic approach. J Biol Chem. 2004 Dec 17;279(51):53266-71. Epub 2004 Oct 13.
USBio References
No references available
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