Reveromycin C CAS 144860-69-5

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R1988-02 Reveromycin C CAS: 144860-69-5

Specifications

References

CAS Number

144860-69-5

Grade

Highly Purified

Molecular Formula

C37H54O11

Molecular Weight

674.8

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

Reveromycin C is a minor analogue of the reveromycin complex isolated from a Streptomyces sp. Published information suggests that reveromycin C exhibits comparable potency to reveromycin A, its butyl homologue. In Microbial Screening Technologies in-house screens Reveromycins C and A had similar biological profiles but Reveromycin C was generally more potent.

Purity: >95% by HPLC

Solubility: Soluble in Methanol, Ethyl acetate, poorly soluble in acids

Related to: Reveromycin A, Reveromycin B, Reveromycin D

Source

Streptomyces sp.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

1. Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities. Takahashi H. et al. J. |Antibiot. 1992, 45, 1414. |2. Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific |inhibitor Reveromycin A. Miyamoto Y. et al. J. Biol. Chem. 2002, 277, 28810.