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S0098-07F Rabbit Anti-SAR1A, ID (GTP-binding Protein SAR1a, COPII-associated Small GTPase, SARA1, SARA, SAR1)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9NR31
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
NP_064535.1
Shipping Temp
Blue Ice
Storage Temp
-20°C

SAR1A is involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity) and required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).

Applications
Suitable for use in ELISA, Western Blot, Indirect Flow Cytometry, and Immunohistochemistry. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 122-149 in the central region of human SAR1A, UniProt Accession #Q9NR31. |Species Sequence Homology: bovine, mouse and porcine
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human SAR1A.
References
1. Morgan,A.R., et.al., Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B(6), 762-770(2007).
USBio References
No references available
Conjugates
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