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S0392-25C Goat Anti-SCARF1 (Scavenger Receptor Class F Member 1, Acetyl LDL Receptor, KIAA0149, MGC47738, Scavenger Receptor Expressed by Endothelial Cells 1, SREC1, SREC-I, SREC)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IC WB
Crossreactivity
Hu
Accession #
NP_003684.2, NP_663325.1, NP_663327.2
Gene ID
8578
Shipping Temp
Blue Ice
Storage Temp
-20°C

Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth.

Applications
Suitable for use in ELISA, Western Blot and Immunocytochemistry. Other applications not tested.
Recommended Dilution
ELISA: 1:64,000 Western Blot: 0.3-1ug/ml, observed in human heart lysates on ~85-90kD bands Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to SELDPKGQHVC, from human SCARF1, at the internal region of the protein (NP_003684.2, NP_663325.1, NP_663327.2).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SCARF1.
References
1. Narazaki M, Segarra M, Hou X, Tanaka T, Li X, Tosato G. Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis. Blood. 2010 Oct 21;116(16):3099-107.
USBio References
No references available
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