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S1000-90V Goat Anti-SERPINB11 (Serpin B11)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
NP_536723.2
Gene ID
89778
Shipping Temp
Blue Ice
Storage Temp
-20°C

Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:8000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to EFSQINQPDSNCT, from SERPINB11, at the internal region of the protein (NP_536723.2).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes SERPINB11. Species sequence homology: Human.
References
1. Askew DJ, Cataltepe S, Kumar V, Edwards C, Pace SM, Howarth RN, Pak SC, Askew YS, Brömme D, Luke CJ, Whisstock JC, Silverman GA. SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change. J Biol Chem. 2007 Aug 24;282(34):24948-60. Epub 2007 Jun 11.
USBio References
No references available
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