SIPA1

Clone Type

Polyclonal

Host

Goat

Source

Human

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Accession #

NP_694985.28, NP_006738.3

Gene ID

6494

Shipping Temp

Blue Ice

Storage Temp

-20°C

GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting it to the putatively inactive GDP-bound state.

Applications

Suitable for use in ELISA and Western Blot Other applications not tested.

Recommended Dilution

ELISA: 1:32,000 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Synthetic peptide corresponding to C-ASKQLGSPTADLA, from human SIPA1, at C-terminal (NP_694985.28, NP_006738.3).

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Purity

Purified by immunoaffinity chromatography.

Specificity

Recognizes human SIPA1.

References

1. Hattori M, Tsukamoto N, Nur-e-Kamal MS, Rubinfeld B, Iwai K, Kubota H, Maruta H, Minato N. Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression. Mol Cell Biol. 1995 Jan;15(1):552-60.

USBio References

No references available

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S1013-69K3 Goat Anti-SIPA1 (Signal-induced Proliferation-associated Protein 1, Sipa-1, GTPase-activating Protein Spa-1, p130 SPA-1, SPA1)

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Crossreactivity

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References

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