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S1014-95H Goat Anti-SNM1 (DNA Cross-link Repair 1A Protein, SNM1 Homolog A, hSNM1, hSNM1A, DCLRE1A, KIAA0086, SNM1A)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
NP_055696.3
Gene ID
9937
Shipping Temp
Blue Ice
Storage Temp
-20°C

May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:8000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to PSPNQKRSSQCKRK, from DCLRE1A, at the internal region of the protein (NP_055696.3).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes DCLRE1A. Species sequence homology: Human.
References
1. Akhter S, Richie CT, Deng JM, Brey E, Zhang X, Patrick C Jr, Behringer RR, Legerski RJ. Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress. Mol Cell Biol. 2004 Dec;24(23):10448-55.
USBio References
No references available
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