Binds to the ANK repeat domain of TNKS1 and TNKS2.
Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:64,000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to KVSTLRESSAMAS-C, from TNKS1BP1, at N-terminal (NP_203754.2).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes TNKS1BP1. Species sequence homology: Human.
References
1. Seimiya H, Smith S. The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182). J Biol Chem. 2002 Apr 19;277(16):14116-26.