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T2223 Teicoplanin Complex CAS: 61036-62-2

Specifications
References
CAS Number
61036-62-2
Grade
Highly Purified
MDL Number
MFCD18433408
Molecular Formula
C₈₈H₉₇Cl₂N₉O₃₃
Molecular Weight
1829.69
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
Teichomycin, Tecoplanin, Targocid, Teicomid, Antibiotic 8327A, DL 507IT, L12507, MDL 507, MW 1900

Teicoplanin complex is family of closely related metabolites produced by Actinoplanes teichomyceticus which possesses potent broad spectrum antibiotic activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. The metabolites share a common glycopeptide core (teicoplanin A3) on which a family of fatty acids varying in length, degree of saturation and branching are linked as amides through one of the aminoglycoside moieties. The major component of the complex is teicoplanin A2 which comprises five major components (teicoplanin A2-1 to A2-5), teicoplanin A3 and four minor components (named teicoplanin RS-1 to RS-4).

Synonyms
Teichomycin, Tecoplanin, Targocid, Teicomid, Antibiotic 8327A, DL 507IT, L12507, MDL 507, MW 1900
Source
Actinoplanes sp. MST-AS5054
CAS No
61036-62-2
Molecular Formula
C₈₈H₉₇Cl₂N₉O₃₃
Molecular Weight
1829.69
Appearance
White solid
Purity
≥95% by HPLC
Solubility
Soluble in H2O.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with H2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
References
1. Teichomycins, new antibiotics from Actinoplanes teichomyceticus nov. sp. Parenti, F., et al., J. Antibiotics 31: 276 (1978). 2. Teicoplanin. Goldstein B. P. et al. In: Glycopeptide antibiotics edited by Nagarajan R. Dekker New York, 273 (1994).
USBio References
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