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T8466-29E Rabbit Anti-TRIM29 (Tripartite Motif-containing Protein 29, Tripartite Motif Containing 29, Ataxia telangiectasia Group D Associated Protein, Ataxia-telangiectasia Group D-associated Protein, ATDC, FLJ36085)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC
Crossreactivity
Hu
Accession #
NP_036233
Shipping Temp
Blue Ice
Storage Temp
-20°C

The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers, which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.

Applications
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended Dilution
ELISA: 1:100-1:1000 Immunohistochemistry (paraffin): 1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptides corresponding to aa569-583 of human TRIM29.
Form
Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
Purity
Purified by Protein G affinity Chromatography.
Specificity
Recognizes human TRIM29. Species sequence homology: mouse, rat, chimpanzee, canine.
References
1. Reymond A et al., EMBO J. 2001 May 1;20(9):2140-51 2. Strausberg RL et al., Proc Natl Acad Sci USA. 2002 Dec 24; 99(26): 16899-903.
USBio References
No references available
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