VPS37C

Clone Type

Polyclonal

Host

Goat

Source

Human

Isotype

IgG

Grade

Affinity Purified

Applications

E IHC WB

Crossreactivity

Accession #

NP_060436.4

Gene ID

55048

Shipping Temp

Blue Ice

Storage Temp

-20°C

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.

Applications

Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution

Peptide ELISA: 1:32,000 Western Blot: 0.03-0.1ug/ml, observed in human duodenum lysates ~38kD band Immunohistochemistry (Paraffin): 3-6ug/ml Requires HIER using sodium citrate buffer pH6.0 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Synthetic peptide corresponding to C-ETLKDKTLQELEELQ, from human VPS37C, at the internal region of the protein (NP_060436.4).

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Purity

Purified by immunoaffinity chromatography.

Specificity

Recognizes human VSP37C.

References

1. Eastman SW, Martin-Serrano J, Chung W, Zang T, Bieniasz PD. Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding. J Biol Chem. 2005 Jan 7;280(1):628-36. Epub 2004 Oct 27.

USBio References

No references available

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V0650-28A Goat Anti-VPS37C (Vacuolar Protein Sorting-associated Protein 37C, hVps37C, ESCRT-I Complex Subunit VPS37C, PML39)

Clone Type

Host

Source

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Shipping Temp

Storage Temp

References

USBio References

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