Vascular Endothelial Growth Factor Receptor 1 (FLT1, fms-like tyrosine kinase) is a receptor for VEGR, VEGFB and PGF. This receptor has a large extracellular domain similar to the other members of the fms family and has tyrosine kinase activity. The VEGF kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
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