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V2130-21B Goat Anti-Vitamin D Binding Protein (VCBP/GC (aa18-30)(Group-specific Component)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_000574.2
Shipping Temp
Blue Ice
Storage Temp
-20°C
vitamin D-binding protein/group specific component, vitamin D-binding protein, vitamin D-binding alpha-globulin, vitamin D binding protein, VDBP, VDBG, DBP/GC, DBP, group-specific component (vitamin D binding protein), GC

The vitamin D binding protein (DBP) is a multifunctional plasma protein that can modulate certain immune and inflammatory responses. The diverse cellular functions of DBP appear to require cell surface binding to mediate these processes. Numerous reports have detected DBP bound to the surface of several cell types and would support the concept of a cell surface binding site for DBP.

Applications
Suitable for use in Peptide ELISA and Western Blot. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA: 1:1000 Western Blot: 0.5-3ug/ml detects ~60kD observed human Lung and Ovary lysates (calculated MW of 52.9kD according to NP_000574.2) Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to ERGRDYEKNKVCK, from the internal region (near the N-Terminus) of human Vitamin D Binding Protein. (NP_000574.2).
Form
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity
Purified by peptide affinity chromatography.
Specificity
Recognizes human Vitamin D Binding Protein. Species Sequence Homology: mouse, rat and canine
References
1. Sandford AJ, Pare PD. Genetic risk factors for chronic obstructive pulmonary disease. Clin Chest Med. 2000 Dec;21(4):633-43. Review.
USBio References
No references available
Conjugates
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