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W1002-70C Rabbit Anti-WBSCR14 (Williams Beuren Syndrome Chromosome Region 14, Williams-Beuren Syndrome Chromosome Region 14 Protein, Carbohydrate Responsive Element Binding Protein, CHREBP, MIO, MLX Interacting Protein-like, MLXIPL, Mlx Interactor, MONDOB, WS Basic Helix-loop-helix Leucine Zipper Protein, WS bHLH, WS-bHLH)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9NP71
Isotype
IgG
Grade
Affinity Purified
Applications
IC IF WB
Crossreactivity
Hu
Accession #
NP_116569.1
Shipping Temp
Blue Ice
Storage Temp
-20°C

ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose. This protein may have relevance to lipid metabolism, obesity, and type II diabetes.

Applications
Suitable for use in Western Blot, Immunocytochemistry and Immunofluorescence. Other applications not tested.
Recommended Dilutions
Immunofluorescence (IC): 1:100-1:500 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to residues 50-150 of human ChREBP protein (NP_116569.1). Species Sequence Homology: rat; 87%
Form
Supplied as a liquid in Tris-citrate/phospate, pH 7.5, 0.01% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human ChREBP. Species Crossreactivity: mouse
References
1. Wang, H Wollheim, CB. J. Biol. Chem. 277: 32746-32752 (2002). 2. Letexier, D., et al. J. Lipid Res. 44:2127-2134 (2003). 3. Stoeckman, AK., et al. J. Biol. Chem. 279:15662-15669 (2004). 4. Iizuka, K., et al. PNAS. 101:7281-7286 (2004). 5. L, Ma., et al. J. Biol. Chem. 280:12019-12027 (2005). 6. Yamashita, Hiromi, et al. PNAS. 98: 9116-9121 (2001).
USBio References
No references available
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