XAB2

Clone Type

Polyclonal

Host

Goat

Source

Human

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Bo Ca Hu Mo Rt

Accession #

NP_064581.2

Gene ID

56949

Shipping Temp

Blue Ice

Storage Temp

-20°C

A novel protein designated XAB2 (XPA-binding protein 2) interacts with XPA, a factor central to both nucleotide excision repair subpathways. Data suggests that XAB2 is a novel component involved in transcription-coupled repair and transcription.

Applications

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution

ELISA: 1:8000 Western Blot: 0.3-1ug/ml, observed in human fibroblast A431 lysates on ~90kD bands Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Synthetic peptide corresponding to C-SVPAAVFGSLKED, from human XAB2, at C-terminal (NP_064581.2).

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Purity

Purified by immunoaffinity chromatography.

Specificity

Recognizes human XAB2. Species sequence homology: Bovine, canine, mouse and rat.

References

1. Nakatsu Y, Asahina H, Citterio E, Rademakers S, Vermeulen W, Kamiuchi S, Yeo JP, Khaw MC, Saijo M, Kodo N, Matsuda T, Hoeijmakers JH, Tanaka K. XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription. J Biol Chem. 2000 Nov 10;275(45):34931-7.

USBio References

No references available

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X0801-01B Goat Anti-XAB2 (Pre-mRNA-splicing factor SYF1, XPA-binding Protein 2, Protein HCNP, HCNP, KIAA1177, SYF1)

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