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002916 Astemizole CAS: 68844-77-9

Specifications
References
CAS Number
68844-77-9
Grade
Highly Purified
Molecular Formula
C28H31FN4O
Molecular Weight
458.57
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine; Astemisan; Hismanal; Histamen; Paralergin; R 42512; R 43512; Retolen; Waruzol;

Nonsedating-type histamine H1-receptor antagonist. Potential for combination therapy with antivancer drugs such as doxorubicin in resistant leukemia. Antihistaminic.

Form
White Solid
Melting Point
>175°C (dec.)
Solubility
Chloroform, Methanol
References
Wauquier, A., et al.: Eur. J. Pharmacol., 72, 245 (1981), Laduron, P.M., et al.: Mol. Pharmacol., 21, 294 (1982), Richards, D.M., et al.: Drugs, 28, 38 (1984), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs., 20, 173 (1991), Ishikawa, M., et al.: Biol. Pharm. Bull., 23, 112 (2000),
USBio References
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