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007080 CP-10447 CAS: 843-93-6

Specifications
References
CAS Number
843-93-6
Grade
Highly Purified
Molecular Formula
C16H13BrN2O
Molecular Weight
329.19
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
3-(4-Bromo-2-methylphenyl)-2-methyl-4(3H)-quinazolinone; CP 10447; 3-(4-Bromo-o-tolyl)-2-methyl-4(3H)-quinazolinone;

An inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study of the mechanisms of apoB secretion and triglyceride-rich lipoprotein assembly.

Form
White Solid
Melting Point
149-151°C
Solubility
DMSO
Pfizer Compound
References
Haghpassand, M. et al.: J. Lipid. Res., 37, 1468 (1996); Pan, M. et al.: J. Biol. chem., 275, 27399 (2000);
USBio References
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