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018620 NVP-AUY 922 CAS: 747412-49-3

Specifications
References
CAS Number
747412-49-3
Grade
Highly Purified
Molecular Formula
C26H31N3O5
Molecular Weight
465.54
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
5-[2,4-Dihydroxy-5-(1-methylethyl)phenyl]-N-ethyl-4-[4-(4-morpholinylmethyl)phenyl]-3-isoxazolecarboxamide;VER 52296; NVP-AUY922;

NVP-AUY 922 is a potent inhibitor of heat shock protein 90 (Hsp90) that prevents the proliferation of a range of human cancer cell lines. NVP-AUY 922 has been shown to enhance the radiation sensitivity of tumor cell lines under hypoxia.

References
Djuzenova, C.S. et al.: Cencer Biol. Ther., 13, 425 (2012); Lee, K.-K. et al.: Cancer Sci., 102, 1388 (2011); Okui, T. et al.: Anticancer Res., 31, 1197 (2011);
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