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021558 trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid CAS: 191282-48-1

Specifications
References
CAS Number
191282-48-1
Grade
Highly Purified
Molecular Formula
C14H22O4
Molecular Weight
254.32
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
(2R,3S)-rel-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid; C 75; trans-C 75

trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a well-known fatty acid synthase (FAS) inhibitor. Studies show that trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a cell cycle arrest inducer in hepatocellular carcinoma (HCC) cell lines. It has also been shown to blocks resistin-induced increases in lipid accumulation by human macrophages.

References
Rae, C. et al.: DIab. Obes. Metab., 10, 1271 (2008); Gao, Y. et al.: Cancer Biol. Ther., 5, 978 (2006); Flavin, R. et al.: Fut. Oncol., 6, 551 (2010);
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