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022834 Vitamin D3 CAS: 67-97-0

Specifications
References
CAS Number
67-97-0
Grade
Highly Purified
Molecular Formula
C27H44O
Molecular Weight
384.64
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
(3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol; Cholecalciferol; Duphafral D3 1000; Delsterol; Deparal;

The vitamin that mediates intestinal calcium absorbtion, bone calcium metabolism and probably, muscle activity. Occurs in and is isolated from fish liver oils. Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.

Form
White to Off-White Solid
Melting Point
82-84°C
Solubility
Acetone, Chloroform, Ethyl Acetate
References
Haussler, R., et al.: J. Biol. Chem., 247, 2328 (1972), Holick, M.F., Rec. Res. Canc. Res., 164, 3 (2003), Palmer, H.G., et al.: Cancer Res., 63, 7799 (2003), Welsh, J., et al.: J. Nutr., 133, 2425S (2003),
USBio References
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