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022911 Ximelagatran CAS: 192939-46-1

Specifications
References
CAS Number
192939-46-1
Grade
Highly Purified
Molecular Formula
C24H35N5O5
Molecular Weight
473.57
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
N-[(1R)-1-Cyclohexyl-2-[(2S)-2-[[[[4-[(hydroxyamino)iminomethyl]phenyl]methyl]amino]carbonyl]-1-azetidinyl]-2-oxoethyl]glycine Ethyl Ester; Exanta; H 376/95;

An orally active direct thrombin inhibitor; prodrug of Melagatran. Antithrombotic.

Form
Off-White Amorphous Solid
Melting Point
134-139°C
Solubility
Chloroform, Methanol
References
Owens, P.K., et al.: J. Pharm. Biomed. Anal., 27, 587 (2002), Kalus, J.S., et al.: Expert Opin. Invest. Drugs, 13, 465 (2004), Boos, C.J., et al.: Eur. J. Int. Med., 16, 267 (2005), Cullberg, M., et al.: Clin. Pharmacol. Ther., 77, 279 (2005),
USBio References
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