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166897 Tri-POC Tenofovir Dimer CAS: 1093279-77-6

Specifications
References
CAS Number
1093279-77-6
Grade
Highly Purified
Molecular Formula
C₃₄H₅₂N₁₀O₁₇P₂
Molecular Weight
934.78
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
5-[[(1R)-2-[6-[[[[9-[(2R)-5-Hydroxy-2,11-dimethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]amino]methyl]amino]-9H-purin-9-yl]-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid 1,9-Bis(1-methylethyl) Ester 5-Oxide

Tri-POC Tenofovir Dimer is a dimer of Tenofovir Disoproxil, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. It is also used in the preparation of phosphocitrate for the treatment of rheumatoid and osteoarthritis in the elderly.

Synonyms
5-[[(1R)-2-[6-[[[[9-[(2R)-5-Hydroxy-2,11-dimethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]amino]methyl]amino]-9H-purin-9-yl]-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid 1,9-Bis(1-methylethyl) Ester 5-Oxide
CAS Number
1093279-77-6
Molecular Formula
C₃₄H₅₂N₁₀O₁₇P₂
Molecular Weight
934.78
Melting Point
66-74°C
Solubility
Methanol (Slightly)
Purity
≥90%
Appearance
White to Pale Beige Solid
Stability
Very Hygroscopic
Storage and Stability
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Turhanen, P. et al.: J. Org. Chem., 72, 1468 (2007);
USBio References
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