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167639 CMPDA (N,N'-1,4-Phenylenedi-2,1-ethanediyl bis-2-propanesulfonamide) CAS: 380607-77-2

Specifications
References
CAS Number
380607-77-2
Grade
Highly Purified
Molecular Formula
C16H28N2O4S2
Molecular Weight
376.53
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C

Solubility
100mM in DMSO and to 50mM in ethanol
Molecular Formula
C16H28N2O4S2
Biological Activity
Positive allosteric modulator of GluR2 receptors (EC50 values are 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assay). Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges.
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Purity
~98%
Form
Supplied as a white solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Timm et al (2011) Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol.Pharmacol. 80 267. PMID: 21543522.
USBio References
No references available
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