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207075 Aurantimycin A CAS: 162478-50-4

Specifications
References
CAS Number
162478-50-4
Grade
Highly Purified
Molecular Formula
C38H64N8O14
Molecular Weight
857
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C

Depsipeptide antibiotic. Active against Gram-positive bacteria. Cytotoxic agent. Nematocide activity. Antiulcer agent. Anti-inflammatory drug (C5a antagonist).

CAS Number
162478-50-4
Source
Streptomyces aurantiacus JA 4570
Formula
C38H64N8O14
Method for Determining Identity
Proton NMR
Solubility
Soluble in chloroform, dichloromethane or DMSO. Poorly soluble in H2O.
Molecular Weight
~857.0
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Streptomyces aurantiacus JA 4570
Purity
~98% (HPLC)
Concentration
Not determined
Form
Supplied as an off-white solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Aurantimycins, new depsipeptide antibiotics from Streptomyces aurantiacus IMET 43917: U. Graefe, et al.; J. Antibiot. 48: 119 (1995). 2. Formation of membrane pores by aurantimycins A and B, new lipopeptide antibiotics from Streptomyces aurantiacus: P. Grigoriev, et al.; Bioelectrochem. Bioenerget. 36: 57 (1995). 3. Pharmacological actions of a new synthetic cyclodepsipeptide, the A83586C-citropeptin hybrid, on complement C5a and G-proteins: E.-S. K. Assem, et al.; Inflamm. Res. 57: 21 (2008)
USBio References
No references available
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