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256093 Octreotide Acetate (SMS 201995, Sandostatin) CAS: 79517-01-4

Specifications
References
CAS Number
79517-01-4
Grade
Highly Purified
Molecular Formula
C49H66N10O10S2
Molecular Weight
1019.24
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
SMS 201995; Sandostatin; D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-Alcohol; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2-7)-disulfide acetate

Octapeptide analog of Somatostatin. A gastric antisecretory agent. Used in treatment of acromegaly.

Synonyms
SMS 201995; Sandostatin; D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-Alcohol; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2-7)-disulfide acetate
CAS No
79517-01-4 Free Base: 83150-76-9
Molecular Formula
C49H66N10O10S2
Molecular Weight
1019.24
Appearance
White to off-white lyophilized powder
Purity (HPLC)
≥99%
Storage and Stability
Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap
References
1. Raynor et al (1993) Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding to linear peptides. Mol.Pharmacol. 43 838. PMID: 8100350. 2. Hoyer et al (1994) Molecular pharmacology of somatostatin receptors. Naunyn Schmiedebergs Arch.Pharmacol. 350 441. PMID: 7870182. 3. Hannon et al (2002) Drug design at peptide receptors. Somatostatin receptor ligands. J.Mol.Neurosci. 18 15.
USBio References
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