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257146 YM 202074 CAS: 299900-84-8

Specifications
CAS Number
299900-84-8
Grade
Highly Purified
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
4°C

High affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. Binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. Inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells). Neuroprotective in vivo.

CAS Number
299900-84-8
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