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269236 Crospovidone CAS: 25249-54-1

Specifications
CAS Number
25249-54-1
Grade
Highly Purified
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C

Crospovidone is a polymer that is used in the production of tablets and capsules. It is a water-soluble polyvinylpyrrolidone, which is obtained by the condensation of vinyl acetate with pyrrolidine. Crospovidone has been shown to have toxicological properties in vitro, but not in vivo. In vitro studies have demonstrated that crospovidone has no effect on cell lysis or human serum. It also does not inhibit dapagliflozin, an inhibitor of sodium glucose cotransporter 2 (SGLT2), which is a therapeutic target for type 2 diabetes mellitus. Crospovidone has been shown to be effective as a tablet binder in combination with other polymers such as carbopol and hydroxypropyl cellulose (HPC).

Synonyms
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CAS No
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Molecular Formula
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Molecular Weight
xxx
Appearance
xxx
Purity
xxx
Melting Point
xxx°C
Solubility
xxx
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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