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270662 2,3-Dihydroxybenzoic Acid CAS: 303-38-8

Specifications
CAS Number
303-38-8
Grade
Highly Purified
Molecular Formula
C7H6O4
Molecular Weight
154.12
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
o-Pyrocatechuic Acid; 1,2-Dihydroxybenzene-3-carboxylic Acid; 3-Hydroxysalicylic Acid; Catecholcarboxylic Acid; DHBA; NSC 27435; Pyrocatechuic Acid

2,3-Dihydroxybenzoic acid is a phenol that has been found in F. inermis, has antifungal and antioxidant activities, and is an active metabolite of the NSAID and COX inhibitor aspirin and its metabolite salicylic acid. It is formed from salicylic acid by the cytochrome P450 (CYP) isoform CYP2E1 in human liver microsomes. It is active against the opportunistic fungi A. fumigatus, A. flavus, A. niger, and Chrysosporium. Dihydroxybenzoic acid (1 µM) reduces apoptosis, increases autophagy, glutathione (GSH) levels, and superoxide dismutase (SOD) activity, and reduces glutathione peroxidase (GPX) activity in primary rat embryonic H9c2 cardiomyocytes under high-glucose and high-palmitic acid conditions as an in vitro model of diabetic cardiomyopathy.

Synonyms
o-Pyrocatechuic Acid; 1,2-Dihydroxybenzene-3-carboxylic Acid; 3-Hydroxysalicylic Acid; Catecholcarboxylic Acid; DHBA; NSC 27435; Pyrocatechuic Acid
CAS No
303-38-8
Molecular Formula
C7H6O4
Molecular Weight
154.12
Purity
≥98%
Appearance
Off-white to pink to pale brown powder
1HNMR Spectrum
Conforms to structure
Water (KF)
As Reported
Melting Point
208-211°C (lit)
Storage and Stability
May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Stable for 6 months after receipt.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
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