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292069 Xanthan Gum, USP/EP/FCC CAS: 11138-66-2

Specifications
CAS Number
11138-66-2
Grade
USP
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C

Xanthan gum is an anionic polysaccharide composed of a β-(1→4)-D-glucopyranose glucan backbone with side chains of (1→3)-α-D-mannopyranose-(2→1)-β-D-glucuronic acid-(4→1)-β-D-mannopyranose on alternating residues. Approximately half of the terminal mannose residues are 4,6-pyruvated while most of the inner mannose residues are 6-acetylated. Its properties make it a useful matrix component for drug delivery systems. It forms stable drug suspensions in aqueous media and soft gels with locust bean gum or guar gum. Xanthan gum mimics the texture of lipids and is used as a control in experiments where signaling pathways initiated by consumption of lipid-containing reagents are investigated in mice.

CAS No
11138-66-2
Purity
91-108% (Assay)
Appearance
Light yellow to light reddish yellow crystals
Viscosity
1400-1600mPas
Elemental Analysis (Theoretical)
≤1.5% (Nitrogen)
Heavy Metals
≤�20mg/kg
Arsenic
≤�2mg/kg
Lead
≤�2mg/kg
Mercury
≤�1mg/kg
Cadmium
≤�1mg/kg
pH
6-8
Mould and Yeast
≤50cfu/g
Loss on Drying
≤12%
Residual Solvents
Isopropyl alcohol: ≤500mg/kg
Coliform Organisms
Negative/25g
E. coli
Negative/25g
Microbial Count
≤1000cfu/g (Total plate count)
Pseudomonas aeruginosa
Negative/g
Salmonella
Negative/25g
Staphylococcus aureus
Negative/g
Particle Size
100% through 60 mesh � 95% through 80 mesh
Organic Volatile Impurities
Conforms to USP test
Related Substances
Pyruvic acid: ≥1.5%
Ash
6.5-16.0%
Other polysaccharides
Conforms EP test
Powder color
60
B. cereus
Negative/g
Enterococcus faecalis
Negative/g
Xanthomonas campestris
Negative/g
Factor Viscosity
1.02-1.45
Pyruvic acid
≥1.5%
Storage and Stability
Store at -20°C. Stable for 6 months after receipt. Hygroscopic. Store under inert gas (e.g. Argon).
Meets or exceeds USP/EP/FCC specifications
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
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