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425338 3-Des-(4-fluorophenyl) 3-(4-Fluorobiphen-3-yl) Aprepitant CAS:

Specifications
Grade
Highly Purified
Molecular Formula
C29H25F7N4O3
Molecular Weight
610.52
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C

3-Des-(4-fluorophenyl) 3-(4-Fluorobiphen-3-yl) is a derivative of Aprepitant (A729800), which is a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

Molecular Formula
C29H25F7N4O3
Molecular Weight
610.52
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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