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431626 4-Chloro-3-fluoroaniline CAS: 367-22-6

Specifications
CAS Number
367-22-6
Grade
Highly Purified
Molecular Formula
C6H5ClFN
Molecular Weight
145.56
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C

4-Chloro-3-fluoroaniline is used in the synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate; a key intermediate towards phosphoindole inhibitors of HIV non-nucleoside reverse transcriptase. 4-Chloro-3-fluoroaniline is also used in the synthesis of 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib (D289540) which is an impurity of the tyrosine kinase inhibitor Gefitinib (G304000).

Molecular Formula
C6H5ClFN
Solubility
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Molecular Weight
145.56
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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