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440377 9-Carboxymethoxymethylguanine CAS: 80685-22-9

Specifications
References
CAS Number
80685-22-9
Grade
Highly Purified
Molecular Formula
C₈H₉N₅O₄
Molecular Weight
239.19
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]acetic Acid; Acyclovir Acid; CMMG; Acetic acid, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-, Acetic acid, [(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]- (9CI)

9-Carboxymethoxymethylguanine is a metabolite of Acyclovir which is an antiviral, orally active acyclic nucleoside with inhibitory activity towards several herpes viruses.

Synonyms
2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]acetic Acid; Acyclovir Acid; CMMG; Acetic acid, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-, Acetic acid, [(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]- (9CI)
CAS No
80685-22-9
Molecular Formula
C₈H₉N₅O₄
Molecular Weight
239.19
Purity
≥95% (HPLC)
Appearance
Light yellow to light brown solid
Solubility
DMSO (Slightly), Methanol (Slightly)
Method for Determining Identity
Proton NMR Spectroscopic and Mass Spectrometric Analysis
Elemental Analysis
As Reported
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C for 6 months after receipt. Hygroscopic. Store under inert atmosphere.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Gunness, P., et al.: Transl. Res., 158, 290 (2011). 2. Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979). 3. Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988). 4. Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992)
USBio References
No references available
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