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441697 Aprepitant-d4 CAS: 1133387-60-6

Specifications
CAS Number
1133387-60-6
Grade
Highly Purified
Molecular Formula
C23H17D4F7N4O3
Molecular Weight
538.45000000000005
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C

Aprepitant-d4 is a labeled analogue of Aprepitant (A729800), A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Aprepitant-d4 is a potential treatment for chemotherapy induced nausea and vomiting.

Molecular Formula
C23H17D4F7N4O3
Solubility
DMSO (Slightly), Methanol (Slightly)
Molecular Weight
538.45000000000005
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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