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441918 Auranofin-13C6 CAS:

Specifications
References
Grade
Highly Purified
Molecular Formula
C₁₄¹³C₆H₃₄AuO₉PS
Molecular Weight
684.44
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
[1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold-13C6; 2,3,4,6-Tetraacetate(1-thio-β-D-glucopyranosato)(triethylphosphine)-gold-13C6; 1-Thio-β-D-glucopyranose 2,3,4,6-Tetraacetate Gold Complex; Aktil-13C6; Auranofin-13C6; Crisinor-13C6; Crisofin-13C6; NSC 32152-13C6; Ridaura-13C6; Ridauran-13C6; SKF 39162-13C6; SKF 39162D-13C6; [(Tetra-O-acetyl-β-D-glucopyranosyl)thio](triethylphosphine)gold-13C6

Auranofin-13C6 is a labelled analogue of Auranofin, a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions related to its inhibition of mitochondrial thioredoxin reductase.

CAS No
Unlabelled: 34031-32-8
Molecular Formula
C₁₄¹³C₆H₃₄AuO₉PS
Molecular Weight
684.44
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Kizu, R., et al.: Chem. Pharm. Bull., 41, 1261 (1993), Itokazu, M., et al.: Clin. Ther., 17, 60 (1995), Kean, W.F., et al.: Br. J. Rheumatol., 36, 560 (1997)
USBio References
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