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445122 Crenolanib CAS: 670220-88-9

Specifications
CAS Number
670220-88-9
Grade
Highly Purified
Molecular Formula
C26H29N5O2
Molecular Weight
443.54
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C

Crenolanib (CP-868569) is a tyrosine kinase inhibitor that acts by specifically inhibiting the receptor tyrosine kinases PDGFRα and PDGFRβ. Crenolanib (CP-868569) inhibits the activity of PDGFRα D842V kinase and prevented the phosphorylation of wild type PDGFRα. Crenolanib (CP-868569) possesses potential antineoplastic activity. Crenolanib is believed to suppress PDGFR-related signal transduction pathways leading to the inhibition of tumor angiogenesis and tumor cell proliferation.

Molecular Formula
C26H29N5O2
Molecular Weight
443.54
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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