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453374 L-Methionine [R,S]-Sulfoximine-13C5 CAS:

Specifications
Grade
Highly Purified
Molecular Formula
13C5H12N2O3S
Molecular Weight
185.19
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C

L-Methionine [R,S]-Sulfoximine-13C5,15N is the isotope labelled analog of L-Methionine [R,S]-Sulfoximine. Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).

Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.
Molecular Formula
13C5H12N2O3S
Solubility
Water (Slightly)
Molecular Weight
185.19
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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