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461251 O-Desmethyl Everolimus CAS: 745779-75-3

Specifications
References
CAS Number
745779-75-3
Grade
Highly Purified
Molecular Formula
C₅₂H₈₁NO₁₄
Molecular Weight
944.2
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
Everolimus EP Impurity C

O-Desmethyl Everolimus is an impurity of Everolimus, a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.

Synonyms
Everolimus EP Impurity C
CAS No
745779-75-3
Molecular Formula
C₅₂H₈₁NO₁₄
Molecular Weight
944.2
Appearance Off-white to pale yellow solid
Purity
≥80%
Melting Point
>100°C (dec.)
Solubility
Chloroform (Slightly), Methanol (Slightly)
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)
USBio References
No references available
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