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461489 Octyl-α-hydroxyglutarate CAS:

Specifications
Grade
Highly Purified
Molecular Formula
C13H24O5
Molecular Weight
260.33
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C

Octyl-α-hydroxyglutarate is a cell-permeable derivative of 2-HG (α-hydroxyglutaric acid). Mutations in isocitrate dehydrogenase 1 (IDH1 and IDH2) associated with certain cancers cause isocitrate to metabolize into 2-HG as opposed α-ketoglutarate, inhibiting α-ketoglutarate-dependant dioxygenases including lysine demethylases and DNA hydroxylases.

This compound is suitable for IDH (isocitrate dehydrogenase) related research.
Molecular Formula
C13H24O5
Molecular Weight
260.33
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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