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465059 (S,S,S)-Aprepitant CAS: 1242175-40-1

Specifications
CAS Number
1242175-40-1
Grade
Highly Purified
Molecular Formula
C23H21F7N4O3
Molecular Weight
534.42999999999995
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C

(S,S,S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

Molecular Formula
C23H21F7N4O3
Molecular Weight
534.42999999999995
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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